Fig. 3
From: Proposal of initial and maintenance dosing regimens with linezolid for renal impairment patients
Boxplots of Cmin at the standard dose in the RI and non-RI groups among the episodes in the TDM group. For each boxplot, the horizontal line across the box within each box represents the median, each box represents the range between the 25th and 75th percentiles, the two whiskers represent the minimum and maximum values that are within 1.5 × IQR, and points beyond the whiskers represent outliers. Closed circles represent Cmin values of the episodes in which dose adjustment was performed, and open circles represent Cmin values of the episodes in which dose adjustment was not performed. Abbreviations: Cmin, trough concentration; RI, renal impairment, TDM, therapeutic drug monitoring