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Table 3 Multivariate conditional logistic regression analysis of variables associated with occurrence of thrombocytopenia

From: Proposal of initial and maintenance dosing regimens with linezolid for renal impairment patients

 

OR (95%CI)

P-value

Male

1.25 (0.52–3.01)

0.62

Body mass index (kg/m2) (per 1-kg/m2 increment)

0.93 (0.72–1.08)

0.25

CLCRC-G ≤ 60 mL/min

2.90 (1.13–7.44)

0.027

Hemoglobin concentration (g/dL) (per 1-g/dL increment)

0.89 (0.72–1.08)

0.23

Platelet count (×103/μL) (per 1.0 × 103/μL increment)

0.993 (0.989–0.997)

0.0002

Bacteraemia

1.44 (0.51–4.01)

0.49

Duration of linezolid treatment (days) (per 1-day increment)

1.010 (0.989–1.031)

0.36

  1. R2 = 0.189
  2. Abbreviations: CLCRC-G creatinine clearance calculated using the Cockcroft-Gault formula