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Table 3 Multivariate conditional logistic regression analysis of variables associated with occurrence of thrombocytopenia

From: Proposal of initial and maintenance dosing regimens with linezolid for renal impairment patients

  OR (95%CI) P-value
Male 1.25 (0.52–3.01) 0.62
Body mass index (kg/m2) (per 1-kg/m2 increment) 0.93 (0.72–1.08) 0.25
CLCRC-G ≤ 60 mL/min 2.90 (1.13–7.44) 0.027
Hemoglobin concentration (g/dL) (per 1-g/dL increment) 0.89 (0.72–1.08) 0.23
Platelet count (×103/μL) (per 1.0 × 103/μL increment) 0.993 (0.989–0.997) 0.0002
Bacteraemia 1.44 (0.51–4.01) 0.49
Duration of linezolid treatment (days) (per 1-day increment) 1.010 (0.989–1.031) 0.36
  1. R2 = 0.189
  2. Abbreviations: CLCRC-G creatinine clearance calculated using the Cockcroft-Gault formula