Fig. 12

The figure shows the effect of arsenite, CoQ₁₀ and DMSA on the liver histopathology. Mice were administered with 15 mg/kg arsenite alone or alongside 200 mg/kg of CoQ₁₀ or 50 mg/kg DMSA independently or in combination. After 45-day post treatment, histological examination of liver tissue was conducted on the five groups; normal control (a), arsenite (b), arsenite+CoQ₁₀ (c), arsenite+DMSA (d) and arsenite+ CoQ₁₀ + DMSA (e). PV-portal vein, CV- central vein, C- congestion. Arrows indicate hepatocyte cytoplasm vacuolation