Fig. 5

The figure shows the effect of arsenite, CoQ₁₀ and DMSA on platelets. Male Swiss mice were treated with 15 mg/kg arsenite daily for 45 days. Two groups of mice were receiving 50 mg/kg DMSA or 200 mg/kg CoQ₁₀ alone while another group of mice were treated using combination of the two. After the 45 days post treatment, blood was obtained by cardiac puncture and the level of platelets (a) and platelecrit (b) determined. One-way ANOVA was used for analysis and Tukey test followed for multiple comparisons. Bars represent ± SEM. Indicated level of significance: *p < 0.05, **p < 0.01, ***p < 0.001. n = 10 mice per group