Skip to main content

Table 2 Values of demographic and biochemical variables before and after calcitriol and placebo interventions

From: The efficacy of calcitriol treatment in non-alcoholic fatty liver patients with different genotypes of vitamin D receptor FokI polymorphism

Variable

Baseline

Week 16

P value

Placebo

Calcitriol

Plasebo

Calcitriol

Group

Time

Group * Time

Weight,kg

83 ± 11.7

83 ± 13.1

82 ± 12.5

83 ± 12.8

0.840

0.746

0.781

BMI, kg/m2

29.1 ± 3.9

29.1 ± 4.7

28.6 ± 4.2

28.8 ± 4.5

0.595

0.754

0.812

WC, cm

101 ± 10.9

100 ± 8.9

100 ± 11.9

100 ± 9.1

0.503

0.854

0.714

HC, cm

107 ± 7.6

106 ± 9.2

106 ± 8.6

106 ± 9.1

0.860

0.512

0.872

TC, mg/dl

188 ± 62.0

187 ± 46.5

187 ± 41.0

179 ± 41.8

0.441

0.827

0.783

TG.mg/dl

180 ± 80.9

194 ± 100.1

178 ± 92.6

177 ± 73.4

0.502

0.814

0.501

HDL-c, mg/dl

40.9 ± 9.3

38 ± 7.9

40.8 ± 11.9

36 ± 9.8

0.001

0.262

0.990

LDL-c, mg/dl

96 ± 25.9

94 ± 23.4

103 ± 22.3

99 ± 27.4

0.551

0.173

0.806

FBS, mg/dl

94 ± 24.0

98 ± 38.4

94 ± 19.9

97 ± 20.0

0.881

0.908

0.813

Insulin, μIU/ml

10.6 ± 5.6

9.2 ± 4.8

10.7 ± 5.7

9.3 ± 4.2

0.737

0.646

0.761

Homa-IR

2.1 ± 0.9

2.0 ± 0.9

2.0 ± 0.8

2.0 ± 0.9

0.546

0.449

0.879

Quicki

0.3 ± 0.03

0.3 ± 0.03

0.3 ± 0.03

0.3 ± 0.03

0.433

0.343

0.672

AST, IU

27 ± 12.6

27 ± 8.7

27 ± 14.5

23 ± 6.1

0.95

0.129

0.713

ALT, IU

47 ± 28.5

43 ± 16.1

35 ± 23.8

30 ± 11.4

0.209

0.000

0.650

GGT, IU

33.5 ± 12.5

35.8 ± 21.3

30.6 ± 21.1

35.9 ± 34

0.245

0.767

0.190

ALK, IU

198 ± 50.1

197 ± 54.9

188 ± 50.7

169 ± 47.3

0.023

0.004

0.030

HSI Index

41.5 ± 5.8

41.3 ± 5.7

38 ± 6.1

38.2 ± 6.0

0.390

0.006

0.647

APRI index

0.3 ± 0.1

0.3 ± 0.1

0.3 ± 0.0

0.2 ± 0.0

0.154

0.242

0.983

Hs-CRP, μg/ml

3.7 ± 3.5

4.5 ± 6.0

3.4 ± 4.2

3.9 ± 5.2

0.320

0.495

0.907

Leptin, ng/ml

17.5 ± 20

14.6 ± 13.9

11.3 ± 9.7

10.6 ± 12.1

0.798

0.001

0.655

Adiponectin, μg/ml

20.5 ± 11.3

21 ± 14.6

18.7 ± 9.7

17.5 ± 10.0

0.57

0.006

0.282

  1. Values are expressed as the mean ± SD. BMI Body mass index, WC Waist circumference, HC Hip circumference, FBS Fasting blood glucose, Homa-IR Homeostatic Model Assessment for Insulin Resistance, HS index Hepatic steatosis index, APRI AST to Platelet Ratio Index, TC total cholesterol, TG Triglyceride, HDL-c High-density lipoproteins- cholesterol, LDL-c Low density lipoprotein- cholesterol, AST aspartate aminotransferase, ALT Alanine aminotransferase, GGT Gamma-glutamyl transferase, ALK Alkaline phosphatase, Hs-CRP High-sensitivity C-reactive protein