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Fig. 5 | BMC Pharmacology and Toxicology

Fig. 5

From: The effective interplay of (non-) selective NSAIDs with neostigmine in animal models of analgesia and inflammation

Fig. 5

Effect of neostigmine with diclofenac or celecoxib on liver function after 5 days from formalin injection. a Serum AST, b serum ALT, c mean of histopathological necro- inflammatory scoring of liver using modified Ishak scoring system and d mean score of other histopathological liver activity indices using NASH Clinical Research Network scoring system. Values are presented as mean ± SD. Data are compared with normal [N] (b), positive control [C] (*), neostigmine [Neo] (@), diclofenac [Diclo] (µ) and celecoxib [Cele] (ɛ), (Mann-Whitney test for comparison) at p < 0.05. [Neo + Diclo] neostigmine + diclofenac; [Neo + Cele] neostigmine + celecoxib

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