Table 3 Model Selection Process^a

1

One compartment model

1098.753

0

YES

2

One compartment model, ETA was not estimated on V

1102.375

3.622

NO

Forward inclusion process

 3

Add WT on CL

1000.624

−69.045

YES

 4

Add SCR on CL

988.23

−12.394

YES

 5

Add co-therapy with ceftriaxone on CL

978.401

−9.829

YES

Backward elimination process

 6

Remove WT on CL

1016.409

44.627

YES

 7

Remove SCR on CL

987.288

14.602

YES

 8

Remove co-therapy with ceftriaxone on CL

981.069

8.187

YES