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Table 1 The influence of bifenthrin on liver mass, serum ALT activity, interleukin 1ß and TNFα in mice livers

From: Subacute poisoning with bifenthrin increases the level of interleukin 1ß in mice kidneys and livers

Group

Liver mass [g] (mean ± SD)

ALT [U/l] (mean ± SD)

Interleukin 1ß in the livers [pg/ml] (mean ± SD)

TNFα in the livers [pg/ml] (mean ± SD

Control females (n = 8)

1.24 ± 0.18

51 ± 12

53.5 ± 23.9

5.81 ± 1.5

1 (n = 8)

1.33 ± 0.16

60 ± 13

54.1 ± 33.5

6.39 ± 1.2

2 (n = 8)

1.35 ± 0.20

80 ± 90

59.1 ± 60.0

7.62 ± 2.4

3 (n = 8)

1.35 ± 0.20

135 ± 20*

99 ± 79.9*

7.90 ± 5.2

  1. *p < 0.05 vs controls
  2. Group 1 - females receiving bifenthrin i.p. at the dose of 1.61 mg/kg for 28 days
  3. Group 2 - females receiving bifenthrin i.p. at the dose of 4.025 mg/kg for 28 days
  4. Group 3 - receiving bifenthrin i.p. at the dose of 8.05 mg/kg for 28 days
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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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