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Table 2 The influence of bifenthrin on kidney mass, creatinine serum concentration, interleukin 1ß and TNFα in mice kidneys

From: Subacute poisoning with bifenthrin increases the level of interleukin 1ß in mice kidneys and livers

Group

Kidney mass [g] (mean ± SD)

Creatinine [mg/dl] (mean ± SD)

Interleukin 1ß in the kidneys [pg/ml] (mean ± SD)

TNFα in the kidneys [pg/ml] (mean ± SD)

Control females (n = 8)

0.16 ± 0.02

0.2 ± 0.00

3.9 ± 2.3

5.45 ± 1.1

1 (n = 8)

0.16 ± 0.01

0.2 ± 0.02

6.8 ± 10.6*

6.04 ± 1.6

2 (n = 8)

0.16 ± 0.03

0.2 ± 0.03

9.8 ± 7.9*

6.39 ± 2.1

3 (n = 8)

0.16 ± 0.04

0.2 ± 0.04

11.2 ± 5.2*

8.50 ± 3.6

  1. *p < 0.05 vs controls
  2. Group 1 - females receiving bifenthrin i.p. at the dose of 1.61 mg/kg for 28 days
  3. Group 2 - females receiving bifenthrin i.p. at the dose of 4.025 mg/kg for 28 days
  4. Group 3 - receiving bifenthrin i.p. at the dose of 8.05 mg/kg for 28 days
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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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