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Table 3 Effect of treatment with alamandine renal oxidative stress markers in DOX-treated rats

From: Protective effect of alamandine on doxorubicin‑induced nephrotoxicity in rats

  Sham Control Ala Dox Dox + Ala
Kidney SOD (U/g tissue) 71.90 ± 10.62 74.42 ± 9.62 69.51 ± 11.96 48.52 ± 14.93**† 59.04 ± 16.09
Kidney MDA (nmol/g tissue) 4.44 ± 1.53 4.46 ± 0.94 5.52 ± 2.61 17.3 ± 5.31**†† 14.87 ± 5.36*†
Kidney GPx Activity
(u/mg protein)
11.17 ± 2.81 11.72 ± 2.09 10.26 ± 2.51 4.91 ± 2.89**† 6.61 ± 2.88
  1. Data are expressed as mean ± SD; n = 7 for each group
  2. P < 0.05, ‎†‎‎†P < 0. 01 compared to the sham‎;‎
  3. *P < 0. 05, ‎**P < 0. 01, ***P < 0.001 compared to the control