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Table 2 Primary outcomes: incidence of CPSP at 3 months

From: Effect of perioperative use of parecoxib on chronic post-surgical pain in elderly patients after hepatectomy: a prospective randomized controlled study

Primary Outcomes

Parecoxib group

Placebo group

RR (95% CI)

P value

CPSP at 3 mo, N (%)

18 (35.3)

24 (44.4)

0.794 (0.493 ~ 1.279)

0.34

Worst-case scenarioa

23 (45.1)

24 (44.4)

1.015 (0.663 ~ 1.552)

0.95

Per-protocol analysisb

18 (39.1)

24 (49.0)

0.799 (0.504 ~ 1.265)

0.33

  1. CPSP chronic post-surgical pain; CI confidence interval; RR relative risk
  2. a All patients lost to follow-up in the parecoxib group developed CPSP, while all patients lost to follow-up in the placebo group did not develop the condition
  3. b Only patients who received allocated intervention and completed follow-up were included in his study