Male | Female | ||||||||
---|---|---|---|---|---|---|---|---|---|
Control | 2500 FU/kg | 7500 FU/kg | 25,000 FU/kg | Control | 2500 FU/kg | 7500 FU/kg | 25,000 FU/kg | ||
D28 | heart | 1.361 ± 0.157 | 1.284 ± 0.100 | 1.353 ± 0.161 | 1.290 ± 0.103 | 0.899 ± 0.109 | 0.877 ± 0.129 | 0.979 ± 0.264 | 0.875 ± 0.076 |
n = 10 | liver | 10.591 ± 1.201 | 10.509 ± 1.030 | 10.769 ± 1.015 | 10.920 ± 1.114 | 6.804 ± 0.701 | 6.636 ± 0.708 | 6.520 ± 0.987 | 6.510 ± 0.541 |
spleen | 0.712 ± 0.160 | 0.725 ± 0.134 | 0.714 ± 0.085 | 0.732 ± 0.128 | 0.500 ± 0.069 | 0.483 ± 0.044 | 0.514 ± 0.051 | 0.473 ± 0.038 | |
kidenys | 2.789 ± 0.198 | 2.600 ± 0.237 | 2.768 ± 0.163 | 2.695 ± 0.208 | 1.747 ± 0.204 | 1.743 ± 0.154 | 1.692 ± 0.221 | 1.709 ± 0.170 | |
thymus | 0.486 ± 0.113 | 0.469 ± 0.073 | 0.497 ± 0.123 | 0.428 ± 0.077 | 0.385 ± 0.108 | 0.353 ± 0.070 | 0.337 ± 0.091 | 0.375 ± 0.073 | |
adrenals | 0.072 ± 0.008 | 0.072 ± 0.013 | 0.073 ± 0.007 | 0.075 ± 0.013 | 0.086 ± 0.010 | 0.083 ± 0.015 | 0.077 ± 0.016 | 0.080 ± 0.016 | |
testis | 3.041 ± 0.368 | 2.903 ± 0.242 | 2.986 ± 0.108 | 3.003 ± 0.261 | – | – | – | – | |
epididymis | 0.902 ± 0.097 | 0.887 ± 0.078 | 0.920 ± 0.074 | 0.894 ± 0.074 | – | – | – | – | |
uterus | – | – | – | – | 0.518 ± 0.074 | 0.527 ± 0.169 | 0.491 ± 0.061 | 0.621 ± 0.184 | |
ovaries | – | – | – | – | 0.090 ± 0.014 | 0.094 ± 0.032 | 0.092 ± 0.011 | 0.096 ± 0.021 | |
brain | 1.967 ± 0.097 | 1.986 ± 0.062 | 1.958 ± 0.077 | 1.984 ± 0.081 | 1.909 ± 0.080 | 1.889 ± 0.072 | 1.905 ± 0.098 | 1.863 ± 0.081 | |
D56 | heart | 1.605 ± 0.203 | 1.535 ± 0.074 | 1.661 ± 0.244 | 1.486 ± 0.016 | 0.915 ± 0.059 | 0.984 ± 0.102 | 1.065 ± 0.134 | 0.959 ± 0.058 |
n = 5 | liver | 13.193 ± 1.495 | 12.676 ± 0.890 | 13.032 ± 1.653 | 12.452 ± 1.449 | 7.476 ± 1.002 | 7.664 ± 0.660 | 7.630 ± 1.037 | 7.374 ± 0.486 |
spleen | 0.793 ± 0.087 | 0.732 ± 0.091 | 0.814 ± 0.059 | 0.798 ± 0.104 | 0.535 ± 0.047 | 0.558 ± 0.048 | 0.518 ± 0.074 | 0.557 ± 0.112 | |
kidenys | 3.447 ± 0.331 | 3.327 ± 0.208 | 3.207 ± 0.466 | 3.409 ± 0.444 | 1.754 ± 0.079 | 1.925 ± 0.202 | 1.931 ± 0.240 | 1.883 ± 0.164 | |
thymus | 0.326 ± 0.071 | 0.341 ± 0.114 | 0.402 ± 0.067 | 0.402 ± 0.026 | 0.259 ± 0.051 | 0.297 ± 0.075 | 0.318 ± 0.045 | 0.252 ± 0.070 | |
adrenals | 0.074 ± 0.011 | 0.076 ± 0.012 | 0.067 ± 0.009 | 0.075 ± 0.018 | 0.081 ± 0.010 | 0.077 ± 0.008 | 0.084 ± 0.012 | 0.080 ± 0.009 | |
testis | 3.329 ± 0.132 | 3.281 ± 0.158 | 3.553 ± 0.501 | 3.271 ± 0.152 | – | – | – | – | |
epididymis | 1.426 ± 0.108 | 1.232 ± 0.041* | 1.391 ± 0.142 | 1.403 ± 0.070 | – | – | – | – | |
uterus | – | – | – | – | 0.590 ± 0.174 | 0.510 ± 0.047 | 0.631 ± 0.034 | 0.653 ± 0.187 | |
ovaries | – | – | – | – | 0.091 ± 0.012 | 0.094 ± 0.015 | 0.086 ± 0.023 | 0.077 ± 0.012 | |
brain | 2.139 ± 0.092 | 2.140 ± 0.076 | 2.153 ± 0.095 | 2.148 ± 0.045 | 1.948 ± 0.037 | 1.964 ± 0.052 | 1.936 ± 0.129 | 1.918 ± 0.072 |