Male | Female | ||||||||
---|---|---|---|---|---|---|---|---|---|
Control | 2500 FU/kg | 7500 FU/kg | 25,000 FU/kg | Control | 2500 FU/kg | 7500 FU/kg | 25,000 FU/kg | ||
D28 | heart | 0.354 ± 0.024 | 0.338 ± 0.019 | 0.351 ± 0.031 | 0.340 ± 0.021 | 0.368 ± 0.029 | 0.359 ± 0.032 | 0.406 ± 0.109 | 0.376 ± 0.036 |
n = 10 | liver | 2.753 ± 0.180 | 2.759 ± 0.167 | 2.798 ± 0.151 | 2.875 ± 0.199 | 2.787 ± 0.137 | 2.721 ± 0.185 | 2.691 ± 0.230 | 2.786 ± 0.157 |
spleen | 0.185 ± 0.037 | 0.190 ± 0.030 | 0.186 ± 0.021 | 0.192 ± 0.026 | 0.205 ± 0.020 | 0.198 ± 0.014 | 0.214 ± 0.024 | 0.203 ± 0.023 | |
kidenys | 0.727 ± 0.033 | 0.683 ± 0.044 | 0.721 ± 0.046 | 0.710 ± 0.034 | 0.715 ± 0.042 | 0.716 ± 0.047 | 0.699 ± 0.048 | 0.731 ± 0.052 | |
thymus | 0.127 ± 0.028 | 0.123 ± 0.018 | 0.129 ± 0.029 | 0.112 ± 0.018 | 0.156 ± 0.033 | 0.145 ± 0.028 | 0.139 ± 0.032 | 0.160 ± 0.029 | |
adrenals | 0.019 ± 0.003 | 0.019 ± 0.004 | 0.019 ± 0.003 | 0.020 ± 0.003 | 0.035 ± 0.004 | 0.034 ± 0.005 | 0.032 ± 0.006 | 0.034 ± 0.005 | |
testis | 0.792 ± 0.080 | 0.765 ± 0.070 | 0.778 ± 0.043 | 0.792 ± 0.059 | – | – | – | – | |
epididymis | 0.235 ± 0.022 | 0.233 ± 0.020 | 0.240 ± 0.026 | 0.237 ± 0.025 | – | – | – | – | |
uterus | – | – | – | – | 0.214 ± 0.036 | 0.215 ± 0.060 | 0.205 ± 0.029 | 0.268 ± 0.087 | |
ovaries | – | – | – | – | 0.037 ± 0.006 | 0.039 ± 0.014 | 0.038 ± 0.006 | 0.041 ± 0.008 | |
brain | 0.513 ± 0.018 | 0.524 ± 0.037 | 0.510 ± 0.031 | 0.524 ± 0.039 | 0.787 ± 0.060 | 0.777 ± 0.042 | 0.793 ± 0.063 | 0.800 ± 0.061 | |
D56 | heart | 0.337 ± 0.020 | 0.319 ± 0.023 | 0.330 ± 0.021 | 0.302 ± 0.020 | 0.345 ± 0.027 | 0.344 ± 0.040 | 0.378 ± 0.027 | 0.338 ± 0.016 |
n = 5 | liver | 2.771 ± 0.151 | 2.633 ± 0.198 | 2.596 ± 0.202 | 2.515 ± 0.171 | 2.820 ± 0.450 | 2.675 ± 0.190 | 2.711 ± 0.226 | 2.600 ± 0.135 |
spleen | 0.168 ± 0.026 | 0.152 ± 0.018 | 0.163 ± 0.022 | 0.161 ± 0.019 | 0.202 ± 0.021 | 0.195 ± 0.012 | 0.184 ± 0.014 | 0.197 ± 0.039 | |
kidenys | 0.725 ± 0.036 | 0.690 ± 0.036 | 0.637 ± 0.049 | 0.689 ± 0.068 | 0.661 ± 0.044 | 0.670 ± 0.041 | 0.687 ± 0.068 | 0.663 ± 0.033 | |
thymus | 0.069 ± 0.013 | 0.071 ± 0.024 | 0.081 ± 0.017 | 0.082 ± 0.009 | 0.098 ± 0.020 | 0.103 ± 0.025 | 0.114 ± 0.015 | 0.088 ± 0.022 | |
adrenals | 0.016 ± 0.003 | 0.016 ± 0.002 | 0.014 ± 0.002 | 0.015 ± 0.003 | 0.030 ± 0.003 | 0.027 ± 0.002 | 0.030 ± 0.007 | 0.028 ± 0.003 | |
testis | 0.703 ± 0.057 | 0.682 ± 0.045 | 0.708 ± 0.066 | 0.664 ± 0.055 | – | – | – | – | |
epididymis | 0.301 ± 0.034 | 0.256 ± 0.013* | 0.277 ± 0.008 | 0.284 ± 0.017 | – | – | – | – | |
uterus | – | – | – | – | 0.223 ± 0.068 | 0.178 ± 0.014 | 0.226 ± 0.019 | 0.230 ± 0.067 | |
ovaries | – | – | – | – | 0.034 ± 0.005 | 0.033 ± 0.005 | 0.031 ± 0.007 | 0.027 ± 0.005 | |
brain | 0.453 ± 0.047 | 0.444 ± 0.007 | 0.431 ± 0.026 | 0.436 ± 0.032 | 0.734 ± 0.036 | 0.687 ± 0.039 | 0.692 ± 0.059 | 0.678 ± 0.037 |