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Table 3 Complete blood count in male rats that received melittin post isoniazid and rifampicin-induced hepatotoxicity

From: Hepatoprotective activity of melittin on isoniazid- and rifampicin-induced liver injuries in male albino rats

  NC T Mel 15 Mel 30 NR
WBCs(×103/μl) 8.75 ± 1.19 5.45 ± 2.09 11.91 ± 1.32b**** 14.13 ± 2.78b**** 9.525 ± 2.00b*
LYM (%) 70.12 ± 7.82 79.23 ± 7.44 75.77 ± 4.19 70.52 ± 9.36 67.67 ± 11.65
MON (%) 4.55 ± 2.20 4.433 ± 2.12 7.117 ± 2.38 5.1 ± 2.18 5.75 ± 1.86
NEU (%) 19.5 ± 4.33 5.633 ± 1.09a** 13.73 ± 2.24 21.17 ± 8.98b** 22.85 ± 9.88b***
EOS (%) 1.15 ± 0.23 1.22 ± 0.26 3.23 ± 1.55b* 3.48 ± 1.43b* 3.65 ± 1.36b**
BAS (%) 0.08 ± 0.04 9.483 ± 4.41a**** 0.15 ± 0.05b**** 0.1 ± 0.0b**** 0.08 ± 0.04b****
RBCs) × 106/μl) 9.033 ± 0.852 7.755 ± 0.26 a** 7.90 ± 0.22 7.952 ± 0.69 7.305 ± 0.34
Hb (g/dl) 15.18 ± 0.80 13.03 ± 0.89a** 14.88 ± 0.32b** 15.17 ± 0.74b** 14.5 ± 1.17b*
Hct (%) 48.78 ± 2.67 40.67 ± 2.28a*** 48.22 ± 1.90b** 49.17 ± 2.47b*** 47.6 ± 4.46b**
MCV (ƒL) 65.3 ± 3.31 52.4 ± 1.69a**** 61.03 ± 2.11b** 62.12 ± 3.81b*** 65.23 ± 5.48b****
MCH (pg) 20.32 ± 0.79 17.52 ± 0.65a*** 18.85 ± 0.35 19.12 ± 1.15b* 19.85 ± 1.27b**
MCHC (g/dL) 31.13 ± 0.41 33.37 ± 0.38a**** 30.90 ± 0.99b**** 30.83 ± 0.36b**** 30.5 ± 0.97b****
PLT (×103/μl) 777 ± 68.9 427.5 ± 146.5a** 827.8 ± 76.3b*** 794.5 ± 130.6b** 607.7 ± 246.4
RDW-CV (%) 18.22 ± 2.1 24.35 ± 2.1a**** 27.1 ± 1.84 28.65 ± 1.93b** 24.75 ± 1.56
  1. Results are expressed as mean ± SD (n = 6)
  2. WBCs White Blood Cells; Lym lymphocytes; Mon: Monocytes; Neu Neutrophils; EOS Eosinophils; Bas Basophils; RBCs Red Blood Cells; Hb Hemoglobin; Hct Hematocrit; MCV Mean corpuscular volume; MCH Mean Corpuscular Hemoglobin; MCHC Mean corpuscular Hemoglobin concentration; PLT platelets; RDW-CV Red blood cell distribution width - Coefficient of Variation
  3. NC control, T Toxic, Mel15 Melittin15μg, Mel 30 Melittin30μg, NR Normal recovery
  4. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001. a: significant Vs NC group, b: significant Vs T group