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Table 1 Esculetin effect on CK-MB, LDH and myocardial Na+/K+ ATPase activity in ISO induced myocardial toxicity

From: Exploring cardioprotective potential of esculetin against isoproterenol induced myocardial toxicity in rats: in vivo and in vitro evidence

 

CK-MB

(IU/L)

LDH

(IU/L)

Na+K+ATPases activity (μmol of Pi/mg/h)

Normal control

85.14 ± 4.374

252.0 ± 10.68

3.285 ± 0.2040

Disease control

336.1 ± 23.43#

449.6 ± 26.48#

1.080 ± 0.158#

Esculetin(10 mg/kg)

144.4 ± 6.399*

319.9 ± 12.77*

2.190 ± 0.099*

Esculetin(20 mg/kg)

121.6 ± 7.470*

257.9 ± 13.33*

2.542 ± 0.303*

  1. All values are shown as mean ± SEM and n = 6. Data analysis done by one way analysis of variance followed by the Tukey multiple comparison tests. # p < 0.05, indicate disease control compared with normal. * p < 0.05, indicate Esculetin treatment compared with disease control group