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Table 1 Esculetin effect on CK-MB, LDH and myocardial Na+/K+ ATPase activity in ISO induced myocardial toxicity

From: Exploring cardioprotective potential of esculetin against isoproterenol induced myocardial toxicity in rats: in vivo and in vitro evidence

  CK-MB
(IU/L)
LDH
(IU/L)
Na+K+ATPases activity (μmol of Pi/mg/h)
Normal control 85.14 ± 4.374 252.0 ± 10.68 3.285 ± 0.2040
Disease control 336.1 ± 23.43# 449.6 ± 26.48# 1.080 ± 0.158#
Esculetin(10 mg/kg) 144.4 ± 6.399* 319.9 ± 12.77* 2.190 ± 0.099*
Esculetin(20 mg/kg) 121.6 ± 7.470* 257.9 ± 13.33* 2.542 ± 0.303*
  1. All values are shown as mean ± SEM and n = 6. Data analysis done by one way analysis of variance followed by the Tukey multiple comparison tests. # p < 0.05, indicate disease control compared with normal. * p < 0.05, indicate Esculetin treatment compared with disease control group