Skip to main content

Table 1 Kinetic parameters for xanthine oxidation in MLS9 system. Constants are expressed as the mean ± SE

From: Plumbagin can potently enhance the activity of xanthine oxidase: in vitro, in vivo and in silico studies

PLB μM

Km μM

Vmax nmol/min/mg

Goodness of fit R2

CLint μL/min/mg

0

7.8 ± 1.0

0.248 ± 0.006

0.972

32

1

4.7 ± 0.5

0.349 ± 0.006

0.980

74

2

4.6 ± 0.5

0.440 ± 0.007

0.984

96

5

4.3 ± 0.5

0.644 ± 0.011

0.983

150

10

4.3 ± 0.4

0.753 ± 0.011

0.987

175

Back to article page

BMC Pharmacology and Toxicology

ISSN: 2050-6511

Contact us