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Table 1 Kinetic parameters for xanthine oxidation in MLS9 system. Constants are expressed as the mean ± SE

From: Plumbagin can potently enhance the activity of xanthine oxidase: in vitro, in vivo and in silico studies

PLB μM Km μM Vmax nmol/min/mg Goodness of fit R2 CLint μL/min/mg
0 7.8 ± 1.0 0.248 ± 0.006 0.972 32
1 4.7 ± 0.5 0.349 ± 0.006 0.980 74
2 4.6 ± 0.5 0.440 ± 0.007 0.984 96
5 4.3 ± 0.5 0.644 ± 0.011 0.983 150
10 4.3 ± 0.4 0.753 ± 0.011 0.987 175
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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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