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Fig. 2 | BMC Pharmacology and Toxicology

Fig. 2

From: Identification of the toxic threshold of 3-hydroxybutyrate-sodium supplementation in septic mice

Fig. 2

Impact of increasing doses of 3HB-Na on blood ion balance, aldosterone and tissue water content. Whole blood taken at sacrifice was assessed for A, Blood Na+; B, Blood pH; C, Blood calculated HCO3; D, Blood K+; E, Blood Cl; and F, plasma aldosterone; G, Water content was determined in brain, liver, lung and muscle. Data are shown as median and interquartile range. Number (n) of animals: white, healthy (n = 14); dashes, PN + glucose (n = 15); PN + 3HB-Na: black, 150 mg/d (n = 16); gray, 180 mg/d (n = 12); dark gray, 225/300 mg/d (n = 8). H: healthy, glc: glucose, PN: parenteral nutrition, mg/d: mg per day

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