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Fig. 4 | BMC Pharmacology and Toxicology

Fig. 4

From: Identification of the toxic threshold of 3-hydroxybutyrate-sodium supplementation in septic mice

Fig. 4

Impact of increasing doses of 3HB-Na on markers associated with kidney damage. a-c Relative gene expression of a, Kim1; b, Ngal; c, Vnn1; and d, blood creatinine levels at sacrifice. Number (n) of animals: white, healthy (n = 14); dashes, PN + glucose (n = 15); PN + 3HB-Na: black, 150 mg/d (n = 16); gray, 180 mg/d (n = 12); dark gray, 225/300 mg/d (n = 8). glc: glucose, PN: parenteral nutrition, mg/d: mg per day

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