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Fig. 6 | BMC Pharmacology and Toxicology

Fig. 6

From: Identification of the toxic threshold of 3-hydroxybutyrate-sodium supplementation in septic mice

Fig. 6

Dose-dependent effect of 3HB-Na supplementation on markers linked to ketone metabolism. Plasma levels of aĀ free fatty acids and bĀ glycerol. Liver relative mRNA expression of cĀ Ppara and dĀ Hmgcs2. a-d Number (n) of animals: white, healthy (nā€‰=ā€‰14); dashes, PNā€‰+ā€‰glucose (nā€‰=ā€‰15); PNā€‰+ā€‰3HB-Na: black, 150Ā mg/d (nā€‰=ā€‰16); gray, 180Ā mg/d (nā€‰=ā€‰12); dark gray, 225/300Ā mg/d (nā€‰=ā€‰8). glc: glucose, PN: parenteral nutrition, mg/d: mg per day

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