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Table.1 Summary of weekly body weight changes (g) of rats in 28-day subacute toxicity study (n = 6)

From: Acute and subacute toxicity evaluation of hydroalcoholic extract from the stem bark of Bois Bande (Parinari campestris Aubl.1772) in rats

 

Males

Females

Weeks

Control

100 mg/kg

300 mg/kg

1000 mg/kg

Control

100 mg/kg

300 mg/kg

1000 mg/kg

Week 1

209.08 ± 25.22

241.18 ± 7.70

244.36 ± 6.06

257.35 ± 7.90

195.79 ± 5.02

192.03 ± 7.81

210.46 ± 5.24

203.38 ± 3.61

Week 2

246.70 ± 27.37

295.43 ± 7.31

294.03 ± 8.83

268.45 ± 12.73

226.06 ± 3.86

221.82 ± 6.71

238.24 ± 6.75

216.88 ± 7.04

Week 3

272.01 ± 27.66

337.37 ± 7.08*

331.38 ± 7.76

296.94 ± 7.09

247.47 ± 4.23

258.98 ± 17.80

248.24 ± 6.75

227.38 ± 5.29

Week 4

289.45 ± 29.13

368.89 ± 9.62*

364.33 ± 7.17*

338.00 ± 7.86

266.61 ± 5.42

259.98 ± 6.76

267.98 ± 7.39

245.04 ± 5.44

Fasted body weight

293.83 ± 29.50

374.89 ± 10.68*

367.83 ± 9.38*

351.17 ± 6.70*

269.50 ± 4.66

256.50 ± 6.05

264.83 ± 5.87

249.00 ± 4.38*

Body weight gain (Week 4–Week 1)

102.90 ± 14.66

127.70 ± 9.95*

120.00 ± 10.53

80.66 ± 8.00

70.82 ± 6.55

67.95 ± 3.35

57.53 ± 7.60

41.66 ± 8.50*

  1. Note. Data was stated as Mean ± Standard Error of the Mean (SEM). *Significantly different from the control group, p < 0.05.
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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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