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Table.4 Summary of the biochemical parameters of the rats in 28-day subacute toxicity study (n = 12)

From: Acute and subacute toxicity evaluation of hydroalcoholic extract from the stem bark of Bois Bande (Parinari campestris Aubl.1772) in rats

Parameters Control 100 mg/kg 300 mg/kg 1000 mg/kg
Serum Na (mmol/L) 142.70 ± 0.49 142.10 ± 0.31 141.90 ± 0.42 142.20 ± 0.42
Serum K (mmol/L) 4.78 ± 0.19 5.13 ± 0.40 4.55 ± 0.14 5.12 ± 0.22
Sodium: Potassium ratio 30.48 ± 1.19 29.20 ± 1.72 31.84 ± 0.99 28.35 ± 1.22
Serum Cl (mmol/L) 106.00 ± 0.66 107.40 ± 0.56 105.80 ± 0.33 106.30 ± 0.37
Urea ((mmol/L) 6.66 ± 0.35 6.18 ± 0.22 6.36 ± 0.24 6.18 ± 0.11
Creatinine (µmol/L) 24.83 ± 1.19 26.07 ± 1.73 25.21 ± 1.14 22.38 ± 0.85
Total Protein (g/dL) 70.75 ± 0.52 72.33 ± 1.03 71.36 ± 0.87 72.50 ± 0.82
Albumin (g/L) 34.50 ± 0.66 35.45 ± 0.49 35.00 ± 0.36 36.42 ± 0.66
Globulin (g/L) 36.25 ± 0.87 36.67 ± 0.77 36.36 ± 0.90 35.82 ± 1.01
Albumin: Globulin ratio 0.96 ± 0.04 0.96 ± 0.02 0.97 ± 0.03 1.03 ± 0.05
Glucose (mmol/L) 6.27 ± 0.28 7.06 ± 0.33 6.92 ± 0.30 7.01 ± 0.59
Cholesterol (mmol/L) 1.48 ± 0.07 1.59 ± 0.09 1.61 ± 0.07 1.36 ± 0.10
ALP (U/L) 220.00 ± 48.98 167.50 ± 12.86 153.20 ± 10.17 170.50 ± 9.61
ALT(U/L) 60.36 ± 4.45 69.36 ± 8.76 60.73 ± 4.75 69.50 ± 6.45
AST (U/L) 172.80 ± 12.07 132.30 ± 17.92 99.45 ± 6.78* 177.20 ± 33.45
Note. Data was stated as Mean ± Standard Error of the Mean (SEM). *Significantly different from the control group, p < 0.05.