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Table 3 Biochemical parameters of rats in different groups

From: Saroglitazar improved hepatic steatosis and fibrosis by modulating inflammatory cytokines and adiponectin in an animal model of non-alcoholic steatohepatitis

Parameters NC HF HF + SARO HF + FENO HF + PIO
ALT (IU/l) 33.47 ± 4.93 69.12 ± 7.33# 37.81 ± 4.51 *** 53.26 ± 8.61** 51.48 ± 9.71**
AST (IU/l) 42.29 ± 4.15 103.91 ± 16.75# 39.08 ± 12.56 *** 66.21 ± 5.01*** 84.73 ± 5.37 *
Leptin (ng/ml) 1.41 ± 0.23 3.12 ± 0.65# 1.86 ± 0.53 *** 2.37 ± 0.41* 2.19 ± 0.31**
Adiponectin (mg/ml) 5.61 ± 0.78 1.55 ± 0.46# 4.70 ± 0.99 *** 3.95 ± 0.83 *** 3.39 ± 1.03 *
  1. Values are expressed as the mean ± S.D. of 7 rats. Between group comparisons was tested by ANOVA followed by Tukey Kramer multiple comparisons test. NC normal control, HF high-fat emulsion, SARO Saroglitazar, FENO Fenofibrate, PIO Pioglitazone.*p < 0.05; **p < 0.01; ***p < 0.001; and ns (nonsignificant) vs. HF. # p < 0.001 vs. NC