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Table 1 Effect of the tested drugs on BGL in alloxan-induced diabetic rats

From: Therapeutic activity of sarpogrelate and dopamine D2 receptor agonists on cardiovascular and renal systems in rats with alloxan-induced diabetes

BGL mg/dL

Groups

Week 1

Week 2

Week 3

Week 4

Normal control group

136.5 ± 18.52

121.33 ± 12.08

119.25 ± 11.35

109 ± 10.92

Diabetic control group

359.75 ± 45.13*

328 ± 141.34*

428.5 ± 121.17*

396.5 ± 80.60*

Diabetic group treated with bromocriptine

191 ± 16.89#

199.25 ± 65.05#

238.25 ± 56.88#

284.25 ± 148.00#

Diabetic group treated with Cabergoline

213.75 ± 37.74#

211.75 ± 38.62#

293 ± 213.15#

280.25 ± 220.48#

Diabetic group treated with sarpogrelate

326.25 ± 93.45

298.25 ± 122.37

393.75 ± 118.77

369.75 ± 43.15

Diabetic group treated with bromocriptine + sarpogrelate

247.75 ± 50.35#

215.5 ± 33.20#

310.25 ± 70.59#

288.25 ± 109.41#

Diabetic group treated with cabergoline + sarpogrelate

196 ± 54.20#

158.75 ± 35.01#

235.5 ± 182.22#

215.75 ± 141.46#

  1. Values shown are means ± SEM; n = 6 rats per group. * P < 0.05, significantly different from the normal control group; # P < 0.05, significantly different from the diabetic control group