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Table 2 Effect of the tested drugs on Kidney Hypertrophic Index in alloxan-induced diabetic rats

From: Therapeutic activity of sarpogrelate and dopamine D2 receptor agonists on cardiovascular and renal systems in rats with alloxan-induced diabetes

Kidney Hypertrophic Index
Groups KHI ( g/g * 1000 )
Normal control group 4.555 ± 0.423
Diabetic control group 6.6125 ± 0.57*
Diabetic group treated with bromocriptine 4.7475 ± 0.33#
Diabetic group treated with cabergoline 4.81 ± 0.49#
Diabetic group treated with sarpogrelate 5.90 ± 0.27
Diabetic group treated with bromocriptine + sarpogrelate 4.715 ± 0.61#
Diabetic group treated with cabergoline + sarpogrelate 4.46 ± 0.48#
  1. Values shown are means ± SEM; n = 6 rats per group. * P < 0.05, significantly different from the normal control group; # P < 0.05, significantly different from the diabetic control group