Skip to main content

Table 2 Effect of the tested drugs on Kidney Hypertrophic Index in alloxan-induced diabetic rats

From: Therapeutic activity of sarpogrelate and dopamine D2 receptor agonists on cardiovascular and renal systems in rats with alloxan-induced diabetes

Kidney Hypertrophic Index

Groups

KHI ( g/g * 1000 )

Normal control group

4.555 ± 0.423

Diabetic control group

6.6125 ± 0.57*

Diabetic group treated with bromocriptine

4.7475 ± 0.33#

Diabetic group treated with cabergoline

4.81 ± 0.49#

Diabetic group treated with sarpogrelate

5.90 ± 0.27

Diabetic group treated with bromocriptine + sarpogrelate

4.715 ± 0.61#

Diabetic group treated with cabergoline + sarpogrelate

4.46 ± 0.48#

  1. Values shown are means ± SEM; n = 6 rats per group. * P < 0.05, significantly different from the normal control group; # P < 0.05, significantly different from the diabetic control group