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Fig. 1 | BMC Pharmacology and Toxicology

Fig. 1

From: Alteration of the gut microbiome in mycophenolate-induced enteropathy: impacts on the profile of short-chain fatty acids in a mouse model

Fig. 1

Mycophenolate-induced enteropathy model. MMF induces significant weight loss after five days of treatment in mice (A), a significant reduction in the caecum weight (B) and a slight decrease of the colon length (C). Histological analysis of proximal colon sections shows a significant decrease in the tissue area (D). Representative microphotographic cross-sections (HES staining) of the proximal colon of control (E) and MMF-treated mice (F). Scale bar equals to 1 mm. Two-way ANOVA followed by post-hoc Bonferroni multiple comparison test (A) and unpaired t-test analysis (B, C, D). **, p < 0.01; ****, p < 0.0001. n = number of mice

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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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