Skip to main content

Table 1 Layout of a combination experiment for synergistic effect of two drugs

From: In vitro growth inhibitory activity of Medicines for Malaria Venture pathogen box compounds against Leishmania aethiopica

Drug 1

4(IC50) = A

2(IC50) = C

(IC50) = E

(IC50)/2 = G

(IC50)/4 = I

Drug 2

4(IC50) = B

2(IC50) = D

(IC50) = F

(IC50)/2 = H

(IC50)/4 = J

Combination

A + B

C + D

E + F

G + H

I + J

  1. The combination index (CI) values were estimated to be CI < 1, =1, and > 1 which indicate synergism, additive, and antagonism, respectively
Back to article page

BMC Pharmacology and Toxicology

ISSN: 2050-6511

Contact us