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Table 1 Layout of a combination experiment for synergistic effect of two drugs

From: In vitro growth inhibitory activity of Medicines for Malaria Venture pathogen box compounds against Leishmania aethiopica

Drug 1 4(IC50) = A 2(IC50) = C (IC50) = E (IC50)/2 = G (IC50)/4 = I
Drug 2 4(IC50) = B 2(IC50) = D (IC50) = F (IC50)/2 = H (IC50)/4 = J
Combination A + B C + D E + F G + H I + J
  1. The combination index (CI) values were estimated to be CI < 1, =1, and > 1 which indicate synergism, additive, and antagonism, respectively