From: Assessment of NSAIDs as potential inhibitors of the fatty acid amide hydrolase I (FAAH-1) using three different primary fatty acid amide substrates in vitro
FAAH-1 kinetics
Substrate
Oleamide
Arachidonamide
Stearoylamide
Km (μM)
177.2 ± 15.5
44.9 ± 7.0
4.6 ± 0.8
Vmax (nmol/min/mg protein)
8.9 ± 1.1
10.1 ± 3.0
2.5 ± 0.6