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Table 2 Potency of indomethacin in the presence of different concentrations of ethanol

From: Assessment of NSAIDs as potential inhibitors of the fatty acid amide hydrolase I (FAAH-1) using three different primary fatty acid amide substrates in vitro

  15% EtOH 20% EtOH 25% EtOH
pIC50 3.4 ± 0.1 3.5 ± 0.1 3.4 ± 0.1
FAAH-1 activity (%) 95 ± 1 78 ± 1 76 ± 4%
  1. Data are mean ± SEM (Standard Error of the Mean) of four separate preparations (n = 4) conducted in triplicate