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Table 2 Potency of indomethacin in the presence of different concentrations of ethanol

From: Assessment of NSAIDs as potential inhibitors of the fatty acid amide hydrolase I (FAAH-1) using three different primary fatty acid amide substrates in vitro

 

15% EtOH

20% EtOH

25% EtOH

pIC50

3.4 ± 0.1

3.5 ± 0.1

3.4 ± 0.1

FAAH-1 activity (%)

95 ± 1

78 ± 1

76 ± 4%

  1. Data are mean ± SEM (Standard Error of the Mean) of four separate preparations (n = 4) conducted in triplicate