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Fig. 2 | BMC Pharmacology and Toxicology

Fig. 2

From: The cytotoxicity and apoptotic effects of verbascoside on breast cancer 4T1 cell line

Fig. 2

Effect of verbascoside on the expression of genes related to apoptosis in 4 T1 cells. a Verbascoside treatment led to the overexpression of caspase3 but was only significant at 130 μM dose. b Verbascoside in a dose-dependent manner significantly increased the expression of Bax gene at 100 μM, 117Μm and, 130 μM. c Verbascoside significantly reduced the expression of Bcl-2 at 100Μm, 117 μM and,. d The effect of verbascoside on the Bax/Bcl-2 ratio. At 100 μM dose ratio (N = 3). *** P < 0.001, ** P < 0.01, * P < 0.05 compared to control

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