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Fig. 3 | BMC Pharmacology and Toxicology

Fig. 3

From: The cytotoxicity and apoptotic effects of verbascoside on breast cancer 4T1 cell line

Fig. 3

Gene expression alteration of Nf-κB, MyD88 and, TLR4 by verbascoside in 4 T1 cells. a Shows verbascoside treatment led to overexpression of TLR4 but was only significant at 130 μM dose (P < 0.05); 1.78 ± 0.32 fold. b Demonstrates verbascoside effectively increased the expression of MyD88 in a dose-dependent manner; 1.44 ± 0.20 fold at 100 μM (P < 0.05), 2.29 ± 0.17 at 117 μM (P < 0.001) and, 2.79 ± 0.07 at 130 μM dose (P < 0.001). c Exhibits the effect of verbascoside treatment on the expression of NF-κB in 4 T1 cells, verbascoside significantly reduced the expression of NF-κB by 0.50 ± 0.13 fold at 117 μM (P < 0.01) and 0.35 ± 0.05 fold at 130 μM concentration (P < 0.001). (N = 3) *** P < 0.001, ** P < 0.01, * P < 0.05 compared to control

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