From: Improved up-and-down procedure for acute toxicity measurement with reliable LD50 verified by typical toxic alkaloids and modified Karber method
Exposure route
Category I
Highest toxicity
Category II
Toxicity
Category III
Moderately toxicity
Category IV
Mildly toxicity
Category V
Low acute toxicity
Oral (mg/kg)
<5
5 ~ 50
51 ~ 300
301 ~ 2000
2001 ~ 5000