Table 15 Comparison of acute toxicity results between iUDP and mKM in three alkaloids
Method | Compound | Category | Animals | Compound (g) | Expense (MOP) | Duration (Day) |
|---|---|---|---|---|---|---|
iUDP | Nicotine | II | 7 | 0.0082 | 1330 | 21 |
Sinomenine hydrochloride | IV | 7 | 0.114 | 1330 | 21 | |
Berberine hydrochloride | V | 9 | 1.9 | 1900 | 24 | |
mKM | Nicotine | II | 74 | 0.0673 | 14,060 | 14 |
Sinomenine hydrochloride | IV | 80 | 1.24 | 15,200 | 14 | |
Berberine hydrochloride | V | 86 | 12.7 | 16,340 | 14 |