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Fig. 11 | BMC Pharmacology and Toxicology

Fig. 11

From: The teratogenic effect of pregabalin on heart, liver and kidney in rats: a light microscopic, electron microscopic and immunohistochemical study

Fig. 11

A photomicrograph of the tissue sections illustrating caspase-3 expression in (A) group Ӏ showing weak caspase-3 immunoexpression (arrow) (B) group ӀӀ showing moderate positive caspase-3 immunoexpression (arrow) (C) group ӀӀӀ showing strong positive caspase-3 immunoexpression (arrow) (D) group Ӏ showing weak caspase-3 immunoexpression (arrow) (E) group ӀӀ showing moderate positive caspase-3 immunoexpression (arrow) (F) group ӀӀӀ showing strong positive caspase-3 immunoexpression (arrow) (G) group Ӏ showing weak caspase-3 immunoexpression (arrow) in the basement membraneʼs renal tubules (T) and in renal glomeruli (G) (H) group ӀӀ showing moderate positive caspase-3 immunoexpression (arrow) in the renal glomerulus (G) as well as in the basement membraneʼs renal tubules (T) (I) group ӀӀӀ showing strong positive caspase-3 immunoexpression (arrow) in the renal glomeruli (G) and the basement membraneʼs renal tubules (T) (caspase-3 immunohistochemical staining × 400, Scale bar = 20 μm)

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