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Fig. 7 | BMC Pharmacology and Toxicology

Fig. 7

From: The teratogenic effect of pregabalin on heart, liver and kidney in rats: a light microscopic, electron microscopic and immunohistochemical study

Fig. 7

A photomicrograph of the cross sections of the kidney in (A) group Ӏ and (B) group ӀӀ showing the thickness of renal cortex (Cx) and medulla (M) (C) group ӀӀӀ showing apparently decrease in the thickness of cortex (Cx) as compared to both groups Ӏ and ӀӀ (D) group Ӏ and (E) group ӀӀ showing the renal glomeruli in immature forms in the outer cortex such as cell condensate (arrow), renal vesicles (V), comma-shaped (C) and S-shaped bodies (S. The renal cortex at a deeper level shows mature glomeruli (G. (F) group ӀӀӀ showing immature renal glomeruli in the outer cortex as seen in groups Ӏ & ӀӀ. The renal cortex at a deeper level displays mature glomeruli (G) with shrunken glomerular capillary tuft (arrow head) and dilated Bowman space (curved arrow. (A-C: H&E × 200, Scale bar = 50 μm & D-F: H&E × 400, Scale bar = 20 μm)

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