Skip to main content

Table 2 Area percent (%) of collagen deposition and area percent (%) of Caspase 3 expression in the examined tissues among the experimental groups

From: The teratogenic effect of pregabalin on heart, liver and kidney in rats: a light microscopic, electron microscopic and immunohistochemical study

Groups Group I Group II Group III P- Value
Parameters
Area %collagen (Heart) 2.97 ± 0.6 5.28 ± 1.1 a,c 27.6 ± 1.9 a,b <  0.0001*
Area %collagen (Liver) 7.48 ± 0.8 17.53 ± 1.1 a,c 26.94 ± 0.9 a,b <  0.0001*
Area % collagen (Kidney) 3.81 ± 0.7 8.35 ± 0.7 a,c 29.72 ± 2.4a, b <  0.0001*
Area % caspase (Heart) 2.47 ± 0.5 9.56 ± 0.9 a,c 20.56 ± 2.7 a,b <  0.0001*
Area % caspase (Liver) 4.34 ± 0.9 12.65 ± 1.2 a,c 18.27 ± 1.9 a,b <  0.0001*
Area % caspase (Kidney) 5.42 ± 1.5 12.04 ± 1.2 a,c 24.60 ± 1.3a, b <  0.0001*
  1. Data are represented as Mean ± SD. * means statistically significant difference
  2. a statistically significanEt when compared to the group I, P <  0.05
  3. b statistically significant when compared to the group II, P <  0.05
  4. c statistically significant when compared to the group III, P < 0.05