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Table 3 APAP concentration above treatment line and laboratory abnormality of the subgroups based on the ingested dose per body weight

From: Evaluation of cut-off values in acute paracetamol overdose following the United Kingdom guidelines

 

≤75 mg/kg (n = 28)

75–200 mg/kg (n = 102)

> 200 mg/kg (n = 42)

Above 100-line

1 (3.6)

17 (16.7)

28 (66.7)

Above 150-line

0 (0.0)

10 (9.8)

24 (54.1)

Acute liver injurya

2 (7.1)

6 (5.9)

1 (2.4)

Increased INRb

0 (0.0)

1 (0.98)

0 (0.0)

Increased creatininec

0 (0.0)

1 (0.98)

1 (2.4)

  1. Table 3. Variables are expressed as n (%) or median (interquartile range). INR International normalized ratio.
  2. a Acute liver injury: Alanine aminotransferase elevation ≥50% during treatment
  3. b Increased INR: INR elevation ≥50% during treatment
  4. c Increased creatinine: creatinine elevation ≥50% during treatment