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Table 1 Top 10 upregulated or downregulated DEGs in HQ-induced K562 cells

From: Identification of potential pathways and microRNA-mRNA networks associated with benzene metabolite hydroquinone-induced hematotoxicity in human leukemia K562 cells

Gene name Description C HQ Log2 (HQ/C) Adjusted P-value
LILRA6 leukocyte immunoglobulin like receptor A6 0.4 6.4 4.17 0.025*
KISS1 KiSS-1 metastasis-suppressor 0.4 6.2 4.15 0.031*
GPR35 G protein-coupled receptor 35 0.7 10.1 3.84 0.006**
CREB3L3 cAMP responsive element binding protein 3 like 3 0.7 8.5 3.58 0.012*
THBS1 thrombospondin 1 31.8 317.2 3.32 0.000***
PI16 peptidase inhibitor 16 6.7 44.9 2.74 0.000***
CCL2 C-C motif chemokine ligand 2 11.7 56.3 2.27 0.000***
IGFBP5 insulin like growth factor binding protein 5 18.4 80.3 2.13 0.031*
CHGB chromogranin B 2.8 11.9 2.07 0.037*
ITGA3 integrin subunit alpha 3 11.3 44.7 1.98 0.000***
KIF19 kinesin family member 19 10.6 1.8 −2.57 0.018*
BMP2 bone morphogenetic protein 2 9.9 1.6 −2.66 0.018*
LRRTM1 leucine rich repeat transmembrane neuronal 1 8.9 1.3 −2.79 0.023*
NMUR1 neuromedin U receptor 1 21.9 2.9 −2.94 0.000***
MARVELD3 MARVEL domain containing 3 7.4 1.0 −2.94 0.037*
ACTL10 actin like 10 12.7 1.5 −3.04 0.002***
LRRC14B leucine rich repeat containing 14B 6.4 0.6 −3.41 0.046*
KRT36 keratin 36 7.1 0.6 −3.47 0.024*
GOLGA8Q golgin subfamily A 5.7 0.3 −4.25 0.045*
HBB hemoglobin subunit beta 370.6 12.0 −4.95 0.029*
  1. * represents P value < 0.05; ** represents P value < 0.01; *** represents P value < 0.005