Fig. 2

Characteristics of Th17 or Tregs in liver after arsenic exposure or Lentinan intervention. A Characteristics of Th17 or Tregs in liver tissues after SA exposure or Lentinan intervention. SA treatment showed the upregulated levels of Th17 or Tregs in liver tissues compared to control, and the intervention with Lentinan led to a significant downregulation of Th17 compared to SA treatment group (P < 0.05), while the change of Tregs was no significant (P > 0.05); B Representative images of Th17 in liver tissues by Flow cytometry analysis; C Representative images of Tregs in liver tissues by Flow cytometry analysis. Data were showed as mean ± SD; n = 5. Th17, Tregs were presented as percentage (%), which was analyzed by ANOVA and independent sample’s t-test; ^*P < 0.05 indicates a significant difference compared with control group; ^#P < 0.05 indicates a significant difference compared with SA treatment group. Abbreviations: Th17, CD4⁺ type 17 helper T cells; Tregs, CD4⁺CD25⁺Foxp3⁺ regulatory T cells