Fig. 4From: Interaction between AhR and HIF-1 signaling pathways mediated by ARNT/HIF-1βCoCl2 in A549 cells reduced the FRET fluorescence signal of pAcGFP1-AhR and pDsRed-Monomer-ARNT. A pAcGFP1-N1-AhR and pDsRed-Monomer-ARNT recombinant plasmids were transfected into A549 cells; 24 h later, the cells were treated with 8 μM BaP for 24 h. B pAcGFP1-AhR and pDsRed-Monomer-ARNT recombinant plasmids were transfected into A549 cells; 24 h later, the cells were treated for 24 h with 8 μM BaP under hypoxic conditions. In A549 cells, BaP enhanced the pAcGFP1-AhR and pDsRed-Monomer-ARNT FRET fluorescent signal in dose-dependent manner,* P < 0.05, ** P < 0.01, n = 3Back to article page