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Fig. 1 | BMC Pharmacology and Toxicology

Fig. 1

From: Cardioprotective effects of sodium thiosulfate against doxorubicin-induced cardiotoxicity in male rats

Fig. 1

Experimental design and timeline. Rats were allocated into control, DOX, STS, and STS + DOX groups. Normal saline (control), 2.5 mg/kg DOX (DOX) and 300 mg/kg STS (STS and STS + DOX groups) were i.p. injected. Thirty minutes later, 2.5 mg/kg DOX was i.p. injected to rats in STS + DOX group. ECG was recorded for all groups before the first injection and after the last injection. Thereafter, all four groups of rats were euthanized, and their heart tissues were collected for H&E staining, oxidative stress markers analysis, and left ventricular papillary muscle contractile assessment

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