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Table 1 Analysis of the parameters of DNA comets of human peripheral blood lymphocytes after their cultivation in the presence of a medical product “Activegel” in vitro

From: Assessment of biosafety and toxicity of hydrophilic gel for implantation in experimental in vitro and in vivo models

Experimental group

Parameters of DNA comets

Tail length, px

% DNA in tail

Tail moment

Peripheral blood lymphocytes + saline, Control

 Donor №1

85.71 ± 5.6

0.25 ± 0.02

0.27 ± 0.03

 Donor №2

97.31 ± 2.0

0.20 ± 0.01

0.25 ± 0.02

 Donor №3

82.07 ± 3.5

0.17 ± 0.01

0.20 ± 0.02

 Donor №4

83.52 ± 6.6

0.20 ± 0.05

0.21 ± 0.01

М ± m

87.2 ± 6.9

0.21 ± 0.03

0.23 ± 0.03

Peripheral blood lymphocytes + “Activegel”

 Donor №1

93.96 ± 3.0

0.22 ± 0.02

0.22 ± 0.01

 Donor №2

72.96 ± 8.5

0.15 ± 0.02

0.23 ± 0.0

 Donor №3

96.97 ± 0.4

0.19 ± 0.02

0.22 ± 0.09

 Donor №4

104.14 ± 17.1

0.27 ± 0.12

0.21 ± 0.04

М ± m

92.0 ± 13.4

0.21 ± 0.05

0.22 ± 0.01

Peripheral blood lymphocytes + H2O2, Positive control

 Donor №1

258.46 ± 15.38

44.46 ± 2.79

70.20 ± 8.79

 Donor №2

269.23 ± 17.59

53.04 ± 5.64

82.76 ± 5.47

 Donor №3

292.31 ± 20.68

52.26 ± 5.49

77.21 ± 6.79

 Donor №4

223.77 ± 26.49

45.24 ± 3.77

69.26 ± 6.49

М ± m

260.76 ± 24.96

48.75 ± 3.92

74.85 ± 5.50