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Fig. 5 | BMC Pharmacology and Toxicology

Fig. 5

From: Identification of 2-(4-N,N-Dimethylaminophenyl)-5-methyl-1-phenethyl-1H-benzimidazole targeting HIV-1 CA capsid protein and inhibiting HIV-1 replication in cellulo

Fig. 5

Inhibition by 696 of early steps in the viral replication cycle by the analysis of reverse transcription by qPCR detecting viral DNA. Each bar displays the mean and SD of 4 wells of qPCR for the HIV-1 pol gene of a representative two independent experiments (see Materials and methods). Stars demonstrate the significance of the difference compared to DMSO-treated samples (unpaired two tails Mann–Whitney test) with *: p < 0.05 and N.S.: non-significant (p > 0.05). Results are expressed as the copy number of pol viral DNA per 1000 copies of β-actin

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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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