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Table 3 Univariate and multivariable-adjusted analyses of factors associated with the occurrence of DDIs

From: Prevalence of potential drug − drug interactions in the cardiothoracic intensive care unit patients in a Chinese tertiary care teaching hospital

Variable

Unadjusted OR (95% CI)

Unadjusted p value

Adjusted OR (95% CI)

Adjusted p value

Gender (reference female)

1.09 (0.51 to 2.35)

0.82

-

-

Age

1.05 (1.02 to 1.07)

 < 0.0001

1.04 (1.01 to 1.07)

0.004

No. of prescribed drugs

1.23 (1.13 to 1.35)

 < 0.0001

1.20 (1.07 to 1.33)

0.001

No. of hospitalization days

1.35 (1.15 to 1.57)

 < 0.0001

1.06 (0.87 to 1.31)

0.56

  1. Hosmer- Lemeshow R2 = 11.9; 8 df; p = 0.16; Cox and Snells’ R2 = 0.19; Nagelkerke’s R.2 = 0.31