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Table 1 Effect of permethrin exposure on the relative organ weights of the rats

From: Long-term low-dose exposure of permethrin induces liver and kidney damage in rats

Parameters

Control

Permethrin

Terminal body weight (g)

479.7 ± 13.3

421.4 ± 13.7*

Brain (g%)

0.437 ± 0.027

0.479 ± 0.036

Heart (g%)

0.275 ± 0.010

0.293 ± 0.010

Liver (g%)

2.94 ± 0.17

2.76 ± 0.27

Spleen (g%)

0.202 ± 0.021

0.205 ± 0.018

Kidneys (g%)

0.667 ± 0.073

0.705 ± 0.025

Testicles (g%)

0.861 ± 0.062

0.875 ± 0.076

Adrenals (mg%)

16.2 ± 3.7

18.2 ± 2.4

  1. Rats were given permethrin (75 mg/kg body weight/day, gavage) daily for 90 consecutive days. The rats in control group received daily an equivalent dose of corn oil (1 ml/kg body weight/day). The body weight of each rat was recorded daily. All rats were anesthetized with pentobarbital sodium and decapitated twenty-four hours after the last administration. Weights of organs were immediately measured after they were isolated from the body. Data are presented as mean ± SD (n = 5). *P < 0.05, compared with the control
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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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