Fig. 2
From: Resveratrol’s neural protective effects for the injured embryoid body and cerebral organoid
The changes of embryoid bodies (EBs) and cerebral organoid (COs) after resveratrol (RSV) treatment. A-E show the control group, D-gal group, RSV-L, RSV-M and RSV-H groups at D5 respectively. F-J show the control group, D-gal group, RSV-L, RSV-M and RSV-H groups at D8 respectively as well. Compared with control group (A, F) at D5 and D8, the size of spheres in the D-gal group (B, G) is decreased sharply. RSV can rescue the development of EB and COs delay, in RSV-L (C, H) groups at D5 and at D8 as well, and make the EB and COs’ size increased compared with that in the D-gal group (B, G), however, RSV’ rescue is not obvious in RSV-M (D, I) and RSV-H (E, J) group, comparing with RSV-L. K, statistical analyses for the EBs diameter are made. In the same age, RSV treatment can increased the size of spheres. A-J, scale bars = 50 μm; Control: the control group; RSV-L: the RSV low-dose group; RSV-M: the RSV medium-dose group; RSV-H: the RSV high-dose group