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Table 1 The characteristics of all subjects, the low-age and high-age groups and male and female groups

From: Development of a particle swarm optimization-backpropagation artificial neural network model and effects of age and gender on pharmacokinetics study of omeprazole enteric-coated tablets in Chinese population

Characteristics

All subjects

Male group

Female group

Low-age group

High-age group

Gender(male/female)

(23/24)

(23/0)

(0/24)

(13/11)

(10/13)

Age(years)

28.6 ± 6.61 (20.0,42.0)

27.6 ± 6.13 (21.0,42.0)

29.2 ± 6.95 (20.0,42.0)

23.3 ± 1.79 (20.0,26.0)

34.3 ± 4.68 (28.0,42.0)

Body mass index (kg∙cm-2)

27.2 ± 1.79 (19.2,25.3)

22.1 ± 1.89 (19.2,25.2)

21.4 ± 1.68 (19.3,25.3)

21.4 ± 1.96 (19.2,24.6)

22.2 ± 1.55 (19.3,25.3)

Hemoglobin count (g∙L-1)

141 ± 14.3 (117,172)

153 ± 7.78 (139,172)

130 ± 9.04 (117,149)

142 ± 13.6 (117,161)

140 ± 15.5 (117,172)

Red blood cell count (1012∙L-1)

4.69 ± 0.44 (3.77,5.52)

4.98 ± 0.28 (4.36,5.43)

4.43 ± 0.37 (3.77,5.52)

4.79 ± 0.40 (3.85,5.52)

4.59 ± 0.47 (3.77,5.43)

White blood cell count (109∙L-1)

5.84 ± 1.23 (4.20,9.10)

6.00 ± 1.17 (4.40,8.80)

5.70 ± 1.32 (4.20,9.10)

5.73 ± 1.38 (4.20,9.10)

5.93 ± 1.11 (4.20,7.90)

Blood platelet count (109∙L-1)

223 ± 52.9 (114,361)

216 ± 49.3 (114,307)

231 ± 57.4 (142,361)

215 ± 50.2 (148,361)

231 ± 56.6 (114,320)

Alanine aminotransferase (U∙L-1)

18.7 ± 3.37 (13.0,28.0)

19.0 ± 3.38 (14.0,26.0)

18.6 ± 3.46 (13.0,28.0)

18.8 ± 2.57 (14.0,25.0)

18.7 ± 4.11 (13.0,28.0)

Aspartate aminotransferase (U∙L-1)

14.7 ± 6.89 (6.00,38.0)

17.5 ± 7.25 (8.00,38.0)

11.9 ± 5.50 (6.00,28.0)

12.4 ± 5.02 (6.00,25.0)

14.1 ± 7.87 (7.00,38.0)

Blood urea nitrogen (mmol∙L-1)

4.14 ± 1.05 (1.30,7.00)

4.60 ± 0.94 (3.10,7.00)

3.69 ± 0.99 (1.30,5.80)

4.12 ± 0.97 (2.50,5.80)

4.17 ± 1.17 (1.30,7.00)

Serum creatinine (μmol∙L-1)

61.9 ± 12.7 (39.0,89.0)

72.3 ± 8.66 (54.0,89.0)

52.5 ± 5.80 (41.0,61.0)

65.1 ± 12.7 (46.0,89.0)

58.9 ± 12.5 (39.0,79.0)

  1. Data are shown as Mean ± SD (min, max)