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Table 4 Protective effect of 2E,2′E) dibutylstannanediyl bis(4-(4-nitrophenyl)amino)-4-oxobut-2-enoate (DTN) and omeprazole against ethanol-induced gastric ulcer rats tissues

From: Pharmacological evaluation of newly synthesized organotin IV complex for antiulcer potential

Treatment (mg/Kg)

Ulcer index ± SEM

% Inhibition

Saline (10 mL/Kg)

0 ± 0

_

Ethanol (1 mL/100 g)

10 ± 0.25###

0

DTN (5 mg/Kg) + Ethanol (1 mL/100 g)

5.9 ± 0.29***

41

DTN (10 mg/Kg) + Ethanol (1 mL/100 g)

4.2 ± 0.37***

58

DTN (30 mg/Kg) + Ethanol (1 mL/100 g)

1 ± 0.27***

90

Omeprazole (20 mg/Kg) + Ethanol (1 mL/100 g)

1 ± 0.22***

90

  1. Data expressed as mean ± SEM (n = 5). One way ANOVA with post-hoc Tukey’s test
  2. ###P < 0.001 vs. saline group, ***P < 0.001 vs. ethanol group