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Fig. 2 | BMC Pharmacology and Toxicology

Fig. 2

From: Beneficial effects of Cyclosporine A in combination with Nortriptyline on germ cell-specific apoptosis, oxidative stress and epididymal sperm qualities following testicular ischemia/reperfusion in rats: a comparative study

Fig. 2

Histological appearances in ipsilateral testes groups: Control, T/D, CsA 1, CsA 5, Nort 2, Nort 10 and CsA + Nort (1 and 2 mg/kg). The ischemic alterations and coagulative necrosis (black arrow) were observed, and the orderly arrangement of germ cells was impaired in T/D group. After treatment with CsA, Nort, and CsA + Nort spermatogenesis was restarted and orderly structure of germ cells with a few mature spermatids was observed within seminiferous tubules (H&E; Scale bar: 50, magnification × 200)

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