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Table 2 Histological evaluation by using MSTD values and Cosentino’s scores 24 h after detorsion

From: Beneficial effects of Cyclosporine A in combination with Nortriptyline on germ cell-specific apoptosis, oxidative stress and epididymal sperm qualities following testicular ischemia/reperfusion in rats: a comparative study

Group

MSTD (µm)

Grade

Control

295.7 ± 11.72***

1

T/D

213.0 ± 13.67

3

CsA 1

253.2 ± 17.80***

2

CsA 5

269.2 ± 18.05***, †††

2

Nort 2

225.8 ± 6.73

2

Nort 10

245.8 ± 10.61***,†

2

CsA 1 + Nort 2

259.7 ± 7.94***, ††

2

  1. ***p < 0.001 compared with T/D group
  2. ††† P < 0.001 compared with CsA 1 mg/kg
  3. †† P < 0.01 compared with CsA 1 mg/kg
  4. † P < 0.05 compared with Nort 2 mg/kg
  5. Cosentino’s score: 1. Minimal or no evidence of injury, 2. Slight injury, 3. Mild injury, 4. Moderate injury
  6. (n = 6)
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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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