Table 6 Analysis of the factors involved in severe CARDs

Age

X² = 3.770, P = 0.152

  Pediatric

7(9.86)

150(19.06)

  Adult

41(57.75)

419(53.24)

  Geriatric

23(32.39)

218(27.70)

Past history

  History of allergy

5(7.04)

2(0.25)

P < 0.0001

  History of smoking

12 (16.90)

20(2.54)

P < 0.0001

  During pregnancy

4 (5.63)

10(1.27)

P = 0.023

  History of liver disease

1(1.41)

5(0.64)

P = 0.405

  None

49

750

Primary disease

  Cardiovascular diseases

29(40.85)

283(35.96)

X² = 3.977, P = 0.046

  Respiratory diseases

10(14.08%)

161(20.46)

X² = 4.302, P = 0.038

  Gynecological diseases

7(9.86%)

112(14.23)

X² = 1.042, P = 0.307

  Digestive system diseases

2(2.82%)

59(7.50)

X² = 2.160, P = 0.142

  Tumors

3(4.23%)

58(7.37)

X² = 0.975, P = 0.323

  Urological diseases

8(11.27%)

32(4.07)

P = 0.120

  Surgical diseases

12(16.90%)

82(10.42)

X² = 2.805, P = 0.094

Route of administration

X² = 5.954, P = 0.015

  Oral

12(16.9)

65(8.26)

  Intravenous

59(83.1)

722(91.74)

Outcome

P < 0.0001

  Recovery

65(91.55)

785(99.75)

  Improvement

6(8.45)

2(0.25)

Drug

  Cefoperazone sodium and sulbactam sodium injection

16

29

X² = , P < 0.0001

  iodixanol injection

14

132

X² = 0.400, P = 0.527

  Levofloxacin lactate and sodium chloride injection

4

11

X² = , P = 0.029

  Piperacillin sodium and tazobactam sodium injection

4

17

X2 = , P = 0.088

  Sanqi Panax notoginseng injection

3

20

X² = , P = 0.429

Ioversol Injection

8

83

X² = 0.036,P = 0.850

  Levofloxacin mesylate and sodium chloride injection

2

25

X² = , P = 1.000

  Amiodarone hydrochloride injection

2

45

X2 = , P = 0.419

  Levofloxacin mesylate injection

4

22

X² = , P = 0.263

  Ceftriaxone sodium injection

4

26

X² = , P = 0.303

  Potassium sodium dehydroandrographolide succinate injection

2

19

X² = , P = 0.690

  Ciprofloxacin lactate injection

2

15

X2 = , P = 0.645

  Safflower injection

2

13

X2 = , P = 0.356